Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones.

ABSTRACT:

Introduction

Major phenolics from licorice roots (Glycyrrhiza sp.) are glycosides of the flavanone liquiritigenin (F) and its 2′-hydroxychalcone isomer, isoliquiritigenin (C). As the F and C contents fluctuate between batches of licorice, both quality control and standardisation of its preparations become complex tasks.

Objective

To characterise the F and C metabolome in extracts from Glycyrrhiza glabra L. and Glycyrrhiza uralensis Fisch. ex DC. by addressing their composition in major F–C pairs and defining the total F:C proportion.

Material and methods

Three types of extracts from DNA-authenticated samples were analysed by a validated UHPLC/UV method to quantify major F and C glycosides. Each extract was characterised by the identity of major F–C pairs and the propo

SUBMITTER: Simmler C 

PROVIDER: S-EPMC4391967 | biostudies-literature | 2014 Jul-Aug

REPOSITORIES: biostudies-literature