Modeling determinants of medication attitudes and poor adherence in early nonaffective psychosis: implications for intervention.

ABSTRACT: We aimed to design a multimodal intervention to improve adherence following first episode psychosis, consistent with current evidence. Existing literature identified medication attitudes, insight, and characteristics of support as important determinants of adherence to medication: we examined medication attitudes, self-esteem, and insight in an early psychosis cohort better to understand their relationships. Existing longitudinal data from 309 patients with early Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, nonaffective psychosis (83% first episode) were analyzed to test the hypothesis that medication attitudes, while meaningfully different from "insight," correlated with insight and self-esteem, and change in each influenced the others. Rosenberg Self-Esteem Scal

SUBMITTER: Drake RJ 

PROVIDER: S-EPMC4393703 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature