Personal history of gallstones and risk of incident psoriasis and psoriatic arthritis in U.S. women.

ABSTRACT:

Background

Metabolic syndrome has been associated with both gallstones and psoriasis, suggesting a potential biological linkage between gallstones and psoriasis. However, the association between gallstones and psoriasis has not yet been studied.

Objectives

To investigate the association between gallstones and psoriasis.

Methods

This was a prospective cohort study [Nurses' Health Study II (1991-2005)]. Women aged 25-42 years who were free from psoriasis at baseline and who responded to a 2005 follow-up questionnaire regarding their diagnosis of psoriasis were included (n = 89,230). The relative risk (RR) of developing psoriasis or psoriatic arthritis (PsA), which were self-reported and validated by supplemental questionnaires, was measured.

Results

In this popul

SUBMITTER: Tong LX 

PROVIDER: S-EPMC4393749 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature