Explaining antiretroviral therapy adherence success among HIV-infected children in rural Uganda: a qualitative study.

ABSTRACT: High adherence is critical for achieving clinical benefits of HIV antiretroviral therapy (ART) and particularly challenging for children. We conducted 35 qualitative interviews with caregivers of HIV-infected Ugandan children who were followed in a longitudinal study of real-time ART adherence monitoring; 18 participants had undetectable HIV RNA, while 17 had detectable virus. Interviews blinded to viral suppression status elicited information on adherence experiences, barriers and facilitators to adherence, and social support. Using an inductive content analytic approach, we identified 'lack of resources,' 'Lazarus effect,' 'caregiver's sense of obligation and commitment,' and 'child's personal responsibility' as categories of influence on adherence, and defined types of caregiver social

SUBMITTER: Olds PK 

PROVIDER: S-EPMC4393764 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature