Age-related cataract in men in the selenium and vitamin e cancer prevention trial eye endpoints study: a randomized clinical trial.

ABSTRACT:

Importance

Observational studies suggest a role for dietary nutrients such as vitamin E and selenium in cataract prevention. However, the results of randomized clinical trials of vitamin E supplements and cataract have been disappointing and are not yet available for selenium.

Objective

To test whether long-term supplementation with selenium and vitamin E affects the incidence of cataract in a large cohort of men.

Design, setting, and participants

The Selenium and Vitamin E Cancer Prevention Trial (SELECT) Eye Endpoints Study was an ancillary study of the Southwest Oncology Group-coordinated SELECT, a randomized placebo-controlled 4-arm trial of selenium and vitamin E conducted among 35,533 men, 50 years and older for African American participants and 55 years and old

SUBMITTER: Christen WG 

PROVIDER: S-EPMC4395006 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature