The method quality of cross-over studies involved in Cochrane Systematic Reviews.

ABSTRACT:

Background

It is possible that cross-over studies included in current systematic reviews are being inadequately assessed, because the current risk of bias tools do not consider possible biases specific to cross-over design. We performed this study to evaluate whether this was being done in cross-over studies included in Cochrane Systematic Reviews (CSRs).

Methods

We searched the Cochrane Library (up to 2013 issue 5) for CSRs that included at least one cross-over trial. Two authors independently undertook the study selection and data extraction. A random sample of the CSRs was selected and we evaluated whether the cross-over trials in these CSRs were assessed according to criteria suggested by the Cochrane handbook. In addition we reassessed the risk of bias of these cross-ov

SUBMITTER: Ding H 

PROVIDER: S-EPMC4395015 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature