Facilitators of adherence to the study pill in the FEM-PrEP clinical trial.

ABSTRACT:

Introduction

FEM-PrEP did not demonstrate a reduction in HIV acquisition because of low study pill adherence. Yet, plasma and intracellular drug concentrations indicated that some participants had evidence of recent pill use. We conducted a follow-up study to identify, among other topics, participants' reasons for taking the study pill.

Methods

Qualitative, semi-structured interviews (SSIs) were conducted with 88 FEM-PrEP participants. Participants were purposefully selected based on their adherence drug concentrations collected during FEM-PrEP and placed into three adherence interview groups: "high," "moderate," and "none/scarce." Participants in the high and moderate groups described reasons why they adhered most or some of the time, including factors that facilitated thei

SUBMITTER: Corneli A 

PROVIDER: S-EPMC4395082 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature