Renal function interferes with copeptin in prediction of major adverse cardiac events in patients undergoing vascular surgery.

ABSTRACT:

Objective

Precise perioperative risk stratification is important in vascular surgery patients who are at high risk for major adverse cardiovascular events (MACE) peri- and postoperatively. In clinical practice, the patient's perioperative risk is predicted by various indicators, e.g. revised cardiac index (RCRI) or modifications thereof. Patients suffering from chronic kidney disease (CKD) are stratified into a higher risk category. We hypothesized that Copeptin as a novel biomarker for hemodynamic stress could help to improve the prediction of perioperative cardiovascular events in patients undergoing vascular surgery including patients with chronic kidney disease.

Methods

477 consecutive patients undergoing abdominal aortic, peripheral arterial or carotid surgery from June

SUBMITTER: Schrimpf C 

PROVIDER: S-EPMC4395325 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature