Association of urinary metal profiles with altered glucose levels and diabetes risk: a population-based study in China.

ABSTRACT:

Background

Elevated heavy metals and fasting plasma glucose (FPG) levels were both associated with increased risk of cardiovascular diseases. However, studies on the associations of heavy metals and essential elements with altered FPG and diabetes risk were limited or conflicting. The objective of this study was to evaluate the potential associations of heavy metals and essential trace elements with FPG and diabetes risk among general Chinese population.

Methods

We conducted a cross-sectional study to investigate the associations of urinary concentrations of 23 metals with FPG, impaired fasting glucose (IFG) and diabetes among 2242 community-based Chinese adults in Wuhan. We used the false discovery rate (FDR) method to correct for multiple hypothesis tests.

Results

A

SUBMITTER: Feng W 

PROVIDER: S-EPMC4395404 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature