Prevalence of human papillomavirus genotypes among African women with normal cervical cytology and neoplasia: a systematic review and meta-analysis.

ABSTRACT:

Background

Several meta-analyses confirmed the five most prevalent human papillomavirus (HPV) strains in women with and without cervical neoplastic diseases are HPV16, 18, 31, 52, and 58. HPV16/18 are the predominant oncogenic genotypes, causing approximately 70% of global cervical cancer cases. The vast majority of the women studied in previous analyses were from Europe, North America, Asia, and most recently Latin America and the Caribbean. Despite the high burden of cervical cancer morbidity and mortality in Africa, a robust meta-analysis of HPV genotype prevalence and distribution in African women is lacking.

Methods and findings

We systematically searched 14 major databases from inception to August 2013 without language restriction, following the Meta-Analysis of Observ

SUBMITTER: Ogembo RK 

PROVIDER: S-EPMC4396854 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature