Impact of diffusion-weighted imaging lesion volume on the success of endovascular reperfusion therapy.

ABSTRACT:

Background and purpose

Diffusion-weighted imaging (DWI) lesion volume is associated with poor outcome after thrombolysis, and it is unclear whether endovascular therapies are beneficial for large DWI lesion. Our aim was to assess the impact of pretreatment DWI lesion volume on outcomes after endovascular therapy, with a special emphasis on patients with complete recanalization.

Methods

We analyzed data collected between April 2007 and November 2011 in a prospective clinical registry. All acute ischemic stroke patients with complete occlusion of internal carotid artery or middle cerebral artery treated by endovascular therapy were included. DWI lesion volumes were measured by the RAPID software. Favorable outcome was defined by modified Rankin Scale of 0 to 2 at 90 days.

R

SUBMITTER: Olivot JM 

PROVIDER: S-EPMC4396870 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature