Visualizing the indefinable: three-dimensional complexity of 'infectious diseases'.

ABSTRACT:

Background

The words 'infection' and 'inflammation' lack specific definitions. Here, such words are not defined. Instead, the ability to visualize host-microbial interactions was explored.

Methods

Leukocyte differential counts and four bacterial species (Staphylococcus aureus, Streptococcus dysgalactiae, Staphylococcus chromogenes, and Escherichia coli) were determined or isolated in a cross-sectional and randomized study conducted with 611 bovine milk samples. Two paradigms were evaluated: (i) the classic one, which measures non-structured (count or percent) data; and (ii) a method that, using complex data structures, detects and differentiates three-dimensional (3D) interactions among lymphocytes (L), macrophages (M), and neutrophils (N).

Results

Classic analyses fa

SUBMITTER: Leitner G 

PROVIDER: S-EPMC4397090 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature