Conventional versus nerve-sparing radical surgery for cervical cancer: a meta-analysis.

ABSTRACT:

Objective

Although nerve-sparing radical surgery (NSRS) is an emerging technique for reducing surgery-related dysfunctions, its efficacy is controversial in patients with cervical cancer. Thus, we performed a meta-analysis to compare clinical outcomes, and urinary, anorectal, and sexual dysfunctions between conventional radical surgery (CRS) and NSRS.

Methods

After searching PubMed, Embase, and the Cochrane Library, two randomized controlled trials, seven prospective and eleven retrospective cohort studies were included with 2,253 patients from January 2000 to February 2014. We performed crude analyses and then conducted subgroup analyses according to study design, quality of study, surgical approach, radicality, and adjustment for potential confounding factors.

Results</

SUBMITTER: Kim HS 

PROVIDER: S-EPMC4397225 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature