Non-invasive differentiation of kidney stone types using X-ray dark-field radiography.

ABSTRACT: Treatment of renal calculi is highly dependent on the chemical composition of the stone in question, which is difficult to determine using standard imaging techniques. The objective of this study is to evaluate the potential of scatter-sensitive X-ray dark-field radiography to differentiate between the most common types of kidney stones in clinical practice. Here, we examine the absorption-to-scattering ratio of 118 extracted kidney stones with a laboratory Talbot-Lau Interferometer. Depending on their chemical composition, microscopic growth structure and morphology the various types of kidney stones show strongly varying, partially opposite contrasts in absorption and dark-field imaging. By assessing the microscopic calculi morphology with high resolution micro-computed tomography measur

SUBMITTER: Scherer K 

PROVIDER: S-EPMC4397641 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature