Plasmodium vivax populations are more genetically diverse and less structured than sympatric Plasmodium falciparum populations.

ABSTRACT:

Introduction

The human malaria parasite, Plasmodium vivax, is proving more difficult to control and eliminate than Plasmodium falciparum in areas of co-transmission. Comparisons of the genetic structure of sympatric parasite populations may provide insight into the mechanisms underlying the resilience of P. vivax and can help guide malaria control programs.

Methodology/principle findings

P. vivax isolates representing the parasite populations of four areas on the north coast of Papua New Guinea (PNG) were genotyped using microsatellite markers and compared with previously published microsatellite data from sympatric P. falciparum isolates. The genetic diversity of P. vivax (He = 0.83-0.85) was higher than that of P. falciparum (He = 0.64-0.77) in all four populations. Modera

SUBMITTER: Jennison C 

PROVIDER: S-EPMC4398418 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature