The microstructural status of the corpus callosum is associated with the degree of motor function and neurological deficit in stroke patients.

ABSTRACT: Human neuroimaging studies and animal models have suggested that white matter damage from ischemic stroke leads to the functional and structural reorganization of perilesional and remote brain regions. However, the quantitative relationship between the transcallosal tract integrity and clinical motor performance score after stroke remains unexplored. The current study employed a tract-based spatial statistics (TBSS) analysis on diffusion tensor imaging (DTI) to investigate the relationship between white matter diffusivity changes and the clinical scores in stroke patients. Probabilistic fiber tracking was also used to identify structural connectivity patterns in the patients. Thirteen ischemic stroke patients and fifteen healthy control subjects participated in this study. TBSS analyses sh

SUBMITTER: Li Y 

PROVIDER: S-EPMC4398463 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature