Molecular investigation of the radiation resistance of edible cyanobacterium Arthrospira sp. PCC 8005.

ABSTRACT: The aim of this work was to characterize in detail the response of Arthrospira to ionizing radiation, to better understand its radiation resistance capacity. Live cells of Arthrospira sp. PCC 8005 were irradiated with ⁶⁰ Co gamma rays. This study is the first, showing that Arthrospira is highly tolerant to gamma rays, and can survive at least 6400 Gy (dose rate of 527 Gy h^-1 ), which identified Arthrospira sp. PCC 8005 as a radiation resistant bacterium. Biochemical, including proteomic and transcriptomic, analysis after irradiation with 3200 or 5000 Gy showed a decline in photosystem II quantum yield, reduced carbon fixation, and reduced pigment, lipid, and secondary metabolite synthesis. Transcription of photo-sensing and signaling pathways, and thiol-based antioxid

SUBMITTER: Badri H 

PROVIDER: S-EPMC4398503 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature