Two-year changes in bone density after Roux-en-Y gastric bypass surgery.

ABSTRACT:

Context

Bariatric surgery is increasingly popular but may lead to metabolic bone disease.

Objective

The objective was to determine the rate of bone loss in the 24 months after Roux-en-Y gastric bypass.

Design and setting

This was a prospective cohort study conducted at an academic medical center.

Participants

The participants were adults with severe obesity, including 30 adults undergoing gastric bypass and 20 nonsurgical controls.

Outcomes

We measured bone mineral density (BMD) at the lumbar spine and proximal femur by quantitative computed tomography (QCT) and dual-energy x-ray absorptiometry at 0, 12, and 24 months. BMD and bone microarchitecture were also assessed by high-resolution peripheral QCT, and estimated bone strength was calculated using mic

SUBMITTER: Yu EW 

PROVIDER: S-EPMC4399296 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature