Pertussis outbreak, southeastern Minnesota, 2012.

ABSTRACT:

Objective

To describe clinical and laboratory findings from the 2012 southeastern Minnesota pertussis outbreak.

Patients and methods

Patients were selected for 2 parts of the study. In the first part, nasopharyngeal swabs from a convenience sample of 265 unique patients were used for both the clinician-requested polymerase chain reaction (PCR) test and culture. B pertussis isolates were tested for macrolide susceptibility and typed using whole genome sequencing and pulsed-field gel electrophoresis. Pertactin gene sequences were analyzed to identify pertactin-deficient B pertussis. In the second part, all patients seen at Mayo Clinic in Rochester, Minnesota, who had PCR results positive for Bordetella pertussis or Bordetella parapertussis between January 1, 2012, and December

SUBMITTER: Theofiles AG 

PROVIDER: S-EPMC4400804 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature