Differential changes in quality of life components over 5 years in chronic obstructive pulmonary disease patients.

ABSTRACT:

Background

The aim of the study was to examine the longitudinal change in quality of life components of patients with chronic obstructive pulmonary disease (COPD).

Methods

In the Hokkaido COPD Cohort Study, 261 subjects were appropriately treated and followed over 5 years with a 74% follow-up rate at the end. The longitudinal changes in St George's Respiratory Questionnaire (SGRQ) scores were annually evaluated with forced expiratory volume in 1 second (FEV1). The subjects were classified into the rapid decliners, slow decliners, and sustainers based on ΔFEV1/year.

Results

The activity component of SGRQ generally deteriorated over time, and its annual decline was the greatest in the rapid decliners (<25th percentile). In contrast, the symptom component improved signif

SUBMITTER: Nagai K 

PROVIDER: S-EPMC4401330 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature