Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems.

ABSTRACT: With the wealth of publications and data available, powerful and transparent computational approaches are required to represent measured data and scientific knowledge in a computable and searchable format. We developed a set of biological network models, scripted in the Biological Expression Language, that reflect causal signaling pathways across a wide range of biological processes, including cell fate, cell stress, cell proliferation, inflammation, tissue repair and angiogenesis in the pulmonary and cardiovascular context. This comprehensive collection of networks is now freely available to the scientific community in a centralized web-based repository, the Causal Biological Network database, which is composed of over 120 manually curated and well annotated biological network models and

SUBMITTER: Boue S 

PROVIDER: S-EPMC4401337 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature