The Sinorhizobium meliloti SyrM regulon: effects on global gene expression are mediated by syrA and nodD3.

ABSTRACT:

Unlabelled

In Sinorhizobium meliloti, three NodD transcriptional regulators activate bacterial nodulation (nod) gene expression. NodD1 and NodD2 require plant compounds to activate nod genes. The NodD3 protein does not require exogenous compounds to activate nod gene expression; instead, another transcriptional regulator, SyrM, activates nodD3 expression. In addition, NodD3 can activate syrM expression. SyrM also activates expression of another gene, syrA, which when overexpressed causes a dramatic increase in exopolysaccharide production. In a previous study, we identified more than 200 genes with altered expression in a strain overexpressing nodD3. In this work, we define the transcriptomes of strains overexpressing syrM or syrA. The syrM, nodD3, and syrA overexpression transcrip

SUBMITTER: Barnett MJ 

PROVIDER: S-EPMC4402393 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature