Genetic association between CD95 rs2234767 polymorphism and cervical cancer risk: a meta analysis.

ABSTRACT:

Background

CD95 rs2234767 polymorphism in the promotor region of CD95 gene has been implicated in several studies of cervical cancer. However, the results have not been conclusively established.

Objective

The main aim of this study was to deal with the controversy with respect to the correlation between CD95 rs2234767 polymorphism and risk of cervical cancer through a meta-analysis.

Methods

Association studies that pertain to CD95 rs2234767 polymorphism and risk of cervical cancer were identified up to May 26, 2014. ORs and 95% CIs were calculated assuming AA versus GG, AA + AG versus GG, AA versus AG + GG, A versus G and AG versus GG genetic models.

Results

A total of 5 case-control studies were included in this meta-analysis. Overall, no significant effect mo

SUBMITTER: Liu P 

PROVIDER: S-EPMC4402820 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature