SMART: physical activity and cerebral metabolism in older people: study protocol for a randomised controlled trial.

ABSTRACT:

Background

Physical activity exerts a variety of long-term health benefits in older adults. In particular, it is assumed to be a protective factor against cognitive decline and dementia.

Methods/design

Randomised controlled assessor blinded 2-armed trial (n = 60) to explore the exercise- induced neuroprotective and metabolic effects on the brain in cognitively healthy older adults. Participants (age ≥ 65), recruited within the setting of assisted living facilities and newspaper advertisements are allocated to a 12-week individualised aerobic exercise programme intervention or a 12-week waiting control group. Total follow-up is 24 weeks. The main outcome is the change in cerebral metabolism as assessed with Magnetic Resonance Spectroscopic Imaging reflecting changes of cerebr

SUBMITTER: Fleckenstein J 

PROVIDER: S-EPMC4403840 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature