Posttraumatic stress disorder, alone or additively with early life adversity, is associated with obesity and cardiometabolic risk.

ABSTRACT:

Background and aims

There is some evidence that posttraumatic stress disorder (PTSD) and early life adversity may influence metabolic outcomes such as obesity, diabetes, and cardiovascular disease. However, whether and how these interact is not clear.

Methods

We analyzed data from a cross-sectional and longitudinal study to determine how PTSD severity influences obesity, insulin sensitivity, and key measures and biomarkers of cardiovascular risk. We then looked at how PTSD and early life adversity may interact to impact these same outcomes.

Results

PTSD severity is associated with increasing risk of obesity, diabetes, and cardiovascular disease, with higher symptoms correlating with higher values of BMI, leptin, fibrinogen, and blood pressure, and lower values of insu

SUBMITTER: Farr OM 

PROVIDER: S-EPMC4404181 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature