Copy number variations in high and low fertility breeding boars.

ABSTRACT:

Background

In this study we applied the extreme groups/selective genotyping approach for identifying copy number variations in high and low fertility breeding boars. The fertility indicator was the calculated Direct Boar Effect on litter size (DBE) that was obtained as a by-product of the national genetic evaluation for litter size (BLUP). The two groups of animals had DBE values at the upper (high fertility) and lower (low fertility) end of the distribution from a population of more than 38,000 boars. Animals from these two diverse phenotypes were genotyped with the Porcine SNP60K chip and compared by several approaches in order to prove the feasibility of our CNV analysis and to identify putative markers of fertility.

Results

We have identified 35 CNVRs covering 36.5 Mb or

SUBMITTER: Revay T 

PROVIDER: S-EPMC4404230 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature