Radioembolization with Yttrium-90 microspheres in hepatocellular carcinoma: Role and perspectives.

ABSTRACT: Transarterial radioembolization (TARE) is a form of brachytherapy in which intra-arterially injected yttrium-90-loaded microspheres serve as a source for internal radiation purposes. On the average, it produces disease control rates exceeding 80% and it is a consolidated therapy for hepatocellular carcinoma (HCC); however, current data are all based on retrospective series or non-controlled prospective studies since randomized controlled trials comparing it with the other liver-directed therapies for intermediate and locally advanced stage HCC are still underway. The data available show that TARE provides similar or even better survival rates when compared to transarterial chemoembolization (TACE). First-line TARE is best indicated for both intermediate-stage patients (staged according to

SUBMITTER: Mosconi C 

PROVIDER: S-EPMC4404379 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature