Strum: an R package for structural modeling of latent variables for general pedigrees.

ABSTRACT:

Background

Structural equation modeling (SEM) is an extremely general and powerful approach to account for measurement error and causal pathways when analyzing data, and it has been used in wide range of applied sciences. There are many commercial and freely available software packages for SEM. However, it is difficult to use any of the packages to analyze general pedigree data, and SEM packages for genetics are limited in their application.

Results

We present the new R package strum to serve the need of a suitable SEM software tool for genetic analysis. It implements a general framework for SEM within the context of general pedigree data. This context requires specialized considerations such as familial correlations and ascertainment. Our package is an extraordinarily flexi

SUBMITTER: Song YE 

PROVIDER: S-EPMC4404673 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature