Intrinsic functional plasticity of the sensory-motor network in patients with cervical spondylotic myelopathy.

ABSTRACT: Several neuroimaging studies have suggested brain reorganisation in patients with cervical spondylotic myelopathy (CSM); however, the changes in spontaneous neuronal activity that are associated with connectedness remain largely unknown. In this study, functional connectivity strength (FCS), a data-driven degree centrality method based on a theoretical approach, was applied for the first time to investigate changes in the sensory-motor network (SMN) at the voxel level. Comparatively, CSM not only showed significantly decreased FCS in the operculum-integrated regions, which exhibited reduced resting-state functional connectivity (rsFC) around the Rolandic sulcus, but it also showed increased FCS in the premotor, primary somatosensory, and parietal-integrated areas, which primarily showed an

SUBMITTER: Zhou FQ 

PROVIDER: S-EPMC4404678 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature