The relationship between sleep-wake cycle and cognitive functioning in young people with affective disorders.

ABSTRACT: Although early-stage affective disorders are associated with both cognitive dysfunction and sleep-wake disruptions, relationships between these factors have not been specifically examined in young adults. Sleep and circadian rhythm disturbances in those with affective disorders are considerably heterogeneous, and may not relate to cognitive dysfunction in a simple linear fashion. This study aimed to characterise profiles of sleep and circadian disturbance in young people with affective disorders and examine associations between these profiles and cognitive performance. Actigraphy monitoring was completed in 152 young people (16-30 years; 66% female) with primary diagnoses of affective disorders, and 69 healthy controls (18-30 years; 57% female). Patients also underwent detailed neuropsycho

SUBMITTER: Carpenter JS 

PROVIDER: S-EPMC4405360 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature