Prevalence, trends and functional impairment associated with reduced estimated glomerular filtration rate and albuminuria among the oldest-old U.S. adults.

ABSTRACT:

Background

The prevalence of reduced estimated glomerular filtration rate (eGFR) among U.S. adults aged 80 years and older increased between 1988 to 1994 and 2005 to 2010. Trends in the prevalence of albuminuria over this time period have not been reported in this population.

Methods

We conducted a cross-sectional analysis of U.S. adults aged 80 years and older in the National Health and Nutrition Examination Survey 1988 to 1994 (n = 1020), 1999 to 2004 (n = 995) and 2005 to 2010 (n = 971) to calculate the prevalence of albuminuria (albumin-to-creatinine ratio [ACR] ≥30 mg/g) by calendar period. The number of U.S. adults aged 80 years and older with elevated ACR and separately reduced eGFR was calculated by calendar period.

Results

Among participants aged 80 years and

SUBMITTER: Bowling CB 

PROVIDER: S-EPMC4406350 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature