Ontology highlight
ABSTRACT:
SUBMITTER: Fushan AA
PROVIDER: S-EPMC4406664 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Fushan Alexey A AA Turanov Anton A AA Lee Sang-Goo SG Kim Eun Bae EB Lobanov Alexei V AV Yim Sun Hee SH Buffenstein Rochelle R Lee Sang-Rae SR Chang Kyu-Tae KT Rhee Hwanseok H Kim Jong-So JS Yang Kap-Seok KS Gladyshev Vadim N VN
Aging cell 20150209 3
Mammals differ more than 100-fold in maximum lifespan, which can be altered in either direction during evolution, but the molecular basis for natural changes in longevity is not understood. Divergent evolution of mammals also led to extensive changes in gene expression within and between lineages. To understand the relationship between lifespan and variation in gene expression, we carried out RNA-seq-based gene expression analyses of liver, kidney, and brain of 33 diverse species of mammals. Our ...[more]