DbVOR: a database system for importing pedigree, phenotype and genotype data and exporting selected subsets.

ABSTRACT:

Background

When studying the genetics of a human trait, we typically have to manage both genome-wide and targeted genotype data. There can be overlap of both people and markers from different genotyping experiments; the overlap can introduce several kinds of problems. Most times the overlapping genotypes are the same, but sometimes they are different. Occasionally, the lab will return genotypes using a different allele labeling scheme (for example 1/2 vs A/C). Sometimes, the genotype for a person/marker index is unreliable or missing. Further, over time some markers are merged and bad samples are re-run under a different sample name. We need a consistent picture of the subset of data we have chosen to work with even though there might possibly be conflicting measurements from multi

SUBMITTER: Baron RV 

PROVIDER: S-EPMC4407391 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature