POU genes are expressed during the formation of individual ganglia of the cephalopod central nervous system.

ABSTRACT:

Background

Among the Lophotrochozoa, cephalopods possess the highest degree of central nervous system (CNS) centralization and complexity. Although the anatomy of the developing cephalopod CNS has been investigated, the developmental mechanisms underlying brain development and evolution are unknown. POU genes encode key transcription factors controlling nervous system development in a range of bilaterian species, including lophotrochozoans. In this study, we investigate the expression of POU genes during early development of the pygmy squid Idiosepius notoides and make comparisons with other bilaterians to reveal whether these genes have conserved or divergent roles during CNS development in this species.

Results

POU2, POU3, POU4 and POU6 orthologs were identified in transcr

SUBMITTER: Wollesen T 

PROVIDER: S-EPMC4407788 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature