Unusual rotavirus genotypes among children with acute diarrhea in Saudi Arabia.

ABSTRACT:

Background

Human rotavirus A (human RV-A) is the most common cause of viral gastroenteritis in infants. The objective of the study was to characterize the G and P genotypes among clinical rotavirus isolates from children with acute diarrhea admitted to a tertiary care hospital in Riyadh, Saudi Arabia.

Methods

From 2011 to 2012, 541 pediatric patients with acute diarrhea were tested for rotavirus infection. RNA extractions from the fecal specimens were done by commercial kit. RT-PCR and sequencing techniques were used to detect the prevalent genotypes. Phylogenetic analysis by Maximum Likelihood method was used to study the clustering of the circulating genotypes.

Results

The data showed that 171/541 (31.6%) faecal samples were positive for human RVA and majority were

SUBMITTER: Aly M 

PROVIDER: S-EPMC4407833 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature