Randomized controlled trial of a mobile phone intervention for improving adherence to naltrexone for alcohol use disorders.

ABSTRACT:

Background

Naltrexone is a front-line treatment for alcohol use disorders, but its efficacy is limited by poor medication adherence. This randomized controlled trial evaluated whether a mobile health intervention could improve naltrexone adherence.

Methods

Treatment-seeking participants with an alcohol use disorder (N = 76) were randomized to intervention and control conditions. All participants received naltrexone (50 mg/day) with a medication event monitoring system (MEMS) and a prepaid smartphone, and received a daily text message querying medication side effects, alcohol use, and craving. Those in the intervention arm received additional medication reminders and adherence assessment via text message.

Results

The primary outcome, proportion of participants with ade

SUBMITTER: Stoner SA 

PROVIDER: S-EPMC4409303 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature