Ontology highlight
ABSTRACT:
SUBMITTER: Vysniauskaite M
PROVIDER: S-EPMC4409380 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Vysniauskaite Milda M Hertfelder Hans-Jörg HJ Oldenburg Johannes J Dreßen Peter P Brettner Stefan S Homann Jürgen J Molderings Gerhard J GJ
PloS one 20150424 4
Diagnosis of mast cell activation disease (MCAD), i.e. systemic mastocytosis (SM) and idiopathic systemic mast cell activation syndrome (MCAS), usually requires demonstration of increased mast cell (MC) mediator release. Since only a few MC mediators are currently established as biomarkers of MCAD, the sensitivity of plasma heparin level (pHL) as an indicator of increased MC activation was compared with that of serum tryptase, chromogranin A and urinary N-methylhistamine levels in 257 MCAD patie ...[more]