Dataset Information
Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering.
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ABSTRACT:
SUBMITTER: Caliari SR
PROVIDER: S-EPMC4409544 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Publications
Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering.
Advanced healthcare materials 20150119 6
A fully 3D biomaterial containing overlapping gradations of structural, compositional, and biomolecular cues as seen in native orthopedic interfaces is described for the first time. A multi-compartment collagen scaffold is created for engineering tendon-bone junctions connected by a continuous interface that can induce spatially specific MSC differentiation down tenogenic and osteogenic lineages without the use of differentiation media. ...[more]