Glomerular filtration rate and albuminuria for detection and staging of acute and chronic kidney disease in adults: a systematic review.

ABSTRACT:

Importance

Because early-stage kidney disease is asymptomatic and is associated with both morbidity and mortality, laboratory measurements are required for its detection.

Objective

To summarize evidence supporting the use of laboratory tests for glomerular filtration rate (GFR) and albuminuria to detect and stage acute kidney injury, acute kidney diseases and disorders, and chronic kidney disease in adults.

Evidence review

We reviewed recent guidelines from various professional groups identified via the National Guideline Clearing House and author knowledge, and systematically searched MEDLINE for other sources of evidence for selected topics.

Findings

The KDIGO (Kidney Disease Improving Global Outcomes) guidelines define and stage acute and chronic kidney dise

SUBMITTER: Levey AS 

PROVIDER: S-EPMC4410363 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature