Long-term nicotine replacement therapy: a randomized clinical trial.

ABSTRACT:

Importance

The US Food and Drug Administration adopted labeling for nicotine patches to allow use beyond the standard 8 weeks. This decision was based in part on data showing increased efficacy for 24 weeks of treatment. Few studies have examined whether the use of nicotine patches beyond 24 weeks provides additional therapeutic benefit.

Objective

To compare 8 (standard), 24 (extended), and 52 (maintenance) weeks of nicotine patch treatment for promoting tobacco abstinence.

Design, setting, and participants

We recruited 525 treatment-seeking smokers for a randomized clinical trial conducted from June 22, 2009, through April 15, 2014, through 2 universities.

Interventions

Smokers received 12 smoking cessation behavioral counseling sessions and were randomized to

SUBMITTER: Schnoll RA 

PROVIDER: S-EPMC4410859 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature