Pathways to suicide-related behavior in offspring of mothers with depression: the role of offspring psychopathology.

ABSTRACT:

Objective

Offspring of mothers with depression are a high-risk group for the development of suicide-related behavior. These offspring are therefore a priority for preventive interventions; however, pathways contributing to risk, including specific aspects of offspring psychopathology, remain unclear. The aim of this study was to examine whether offspring symptoms of major depressive disorder (MDD), generalized anxiety disorder (GAD), disruptive behavior disorder (DBD), attention-deficit/hyperactivity disorder (ADHD), and alcohol abuse independently mediate the association between maternal depression and offspring suicide-related behavior.

Method

Data were used from a population-based birth cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC). Three distinct c

SUBMITTER: Hammerton G 

PROVIDER: S-EPMC4411216 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature