MiR-146a rs2910164 G/C polymorphism and gastric cancer susceptibility: a meta-analysis.

ABSTRACT:

Background

Evidence has shown that single nucleotide polymorphism located in pre-miRNA or mature microRNA may modify various biological processes and affect the processing of carcinogenesis. Published results about the association between miR-146a rs2910164 G/C polymorphism and human gastric cancer susceptibility are inconclusive. The aim of this study was to acquire a more precise effect of the association between the miR-146a rs2910164 polymorphism and gastric risk by meta-analysis.

Methods

Eligible genetic association studies were searched from PubMed, Web of Knowledge and Chinese Biomedicine Database on human subject. Quantitative data synthesis was conducted for the associations of miR-146a rs2910164 G/C polymorphism with susceptibility to gastric cancer.

Results

SUBMITTER: Xu Z 

PROVIDER: S-EPMC4411698 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature