Genetic and environmental risk assessment and colorectal cancer screening in an average-risk population: a randomized trial.

ABSTRACT:

Background

New methods are needed to improve health behaviors, such as adherence to colorectal cancer (CRC) screening. Personalized genetic information to guide medical decisions is increasingly available. Whether such information motivates behavioral change is unknown.

Objective

To determine whether individualized genetic and environmental risk assessment (GERA) of CRC susceptibility improves adherence to screening in average-risk persons.

Design

2-group, randomized, controlled trial. (ClinicalTrials.gov: NCT0087360).

Setting

4 medical school-affiliated primary care practices.

Participants

783 participants at average risk for CRC who were not adherent to screening at study entry.

Intervention

Participants were randomly assigned to usual care or G

SUBMITTER: Weinberg DS 

PROVIDER: S-EPMC4412019 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature