Extrastriate visual cortex reorganizes despite sequential bilateral occipital stroke: implications for vision recovery.

ABSTRACT: The extent of visual cortex reorganization following injury remains controversial. We report serial functional magnetic resonance imaging (fMRI) data from a patient with sequential posterior circulation strokes occurring 3 weeks apart, compared with data from an age-matched healthy control subject. At 8 days following a left occipital stroke, contralesional visual cortical activation was within expected striate and extrastriate sites, comparable to that seen in controls. Despite a further infarct in the right (previously unaffected hemisphere), there was evolution of visual cortical reorganization progressed. In this patient, there was evidence of utilization of peri-infarct sites (right-sided) and recruitment of new activation sites in extrastriate cortices, including in the lateral middl

SUBMITTER: Brodtmann A 

PROVIDER: S-EPMC4412053 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature