Nanofibrous hydrogels with spatially patterned biochemical signals to control cell behavior.

ABSTRACT: The ability to spatially pattern biochemical signals into nanofibrous materials using thiol-ene reactions of thiolated molecules to presented norbornene groups is demonstrated. This approach is used to pattern three molecules independently within one scaffold, to pattern molecules through the depth of a scaffold, and to spatially control cell adhesion and morphology.

SUBMITTER: Wade RJ 

PROVIDER: S-EPMC4412590 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature