Level and determinants of kidney function in a South Asian population in Pakistan.

ABSTRACT:

Background

People of South Asian origin are at high risk of chronic kidney disease. Some have suggested that the usual level of glomerular filtration rate (GFR) in South Asians may be lower than in populations of European origin. However, measured GFR in a general adult population of South Asian origin has not been studied.

Design

Cross-sectional observational study.

Setting & participants

530 patients 40 years or older randomly selected from communities in Karachi, Pakistan, using multistage cluster sampling. Patients with both diabetes and hypertension were excluded.

Predictor

Age, sex, diabetes, and hypertension.

Outcome

Measured GFR using urinary clearance of inulin.

Results

Mean age of participants was 49.7 ± 9.5 (standard deviation [SD]) yea

SUBMITTER: Jafar TH 

PROVIDER: S-EPMC4414013 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature