Pdb-care (PDB carbohydrate residue check): a program to support annotation of complex carbohydrate structures in PDB files.

ABSTRACT:

Background

Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic potential. Knowledge of the 3D structure of glycans is a prerequisite for a complete understanding of their biological functions. The largest source of biomolecular 3D structures is the Protein Data Bank. However, about 30% of all 1663 PDB entries (version September 2003) containing carbohydrates comprise errors in glycan description. Unfortunately, no software is currently available which aligns the 3D information with the reported assignments. It is the aim of this work to fill this gap.

Results

The pdb-care program http://www.glycosciences.de/tools/pdb-care/ is able to identify and assign carbohydrate

SUBMITTER: Lutteke T 

PROVIDER: S-EPMC441419 | biostudies-literature | 2004 Jun

REPOSITORIES: biostudies-literature