Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.

ABSTRACT: The inability to visualize the true extent of cancers represents a significant challenge in many areas of oncology. The margins of most cancer types are not well demarcated because the cancer diffusely infiltrates the surrounding tissues. Furthermore, cancers may be multifocal and characterized by the presence of microscopic satellite lesions. Such microscopic foci represent a major reason for persistence of cancer, local recurrences, and metastatic spread, and are usually impossible to visualize with currently available imaging technologies. An imaging method to reveal the true extent of tumors is desired clinically and surgically. We show the precise visualization of tumor margins, microscopic tumor invasion, and multifocal locoregional tumor spread using a new generation of surface-enha

SUBMITTER: Harmsen S 

PROVIDER: S-EPMC4414254 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature