Multivendor implementation and comparison of volumetric whole-brain echo-planar MR spectroscopic imaging.

ABSTRACT:

Purpose

To assess volumetric proton MR spectroscopic imaging (MRSI) of the human brain on multivendor MRI instruments.

Methods

Echo-planar spectroscopic imaging was developed on instruments from three manufacturers, with matched specifications and acquisition protocols that accounted for differences in sampling performance, radiofrequency (RF) power, and data formats. Intersite reproducibility was evaluated for signal-normalized maps of N-acetylaspartate (NAA), creatine (Cre), and choline using phantom and human subject measurements. Comparative analyses included metrics for spectral quality, spatial coverage, and mean values in atlas-registered brain regions.

Results

Intersite differences for phantom measurements were less than 1.7% for individual metabolites and les

SUBMITTER: Sabati M 

PROVIDER: S-EPMC4414683 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature