Changes in lens opacities on the age-related eye disease study grading scale predict progression to cataract surgery and vision loss: age-related eye disease study report no. 34.

ABSTRACT: PURPOSE:To investigate whether the 2-year change in lens opacity severity on the Age-Related Eye Disease Study (AREDS) lens grading scale predicts progression to cataract surgery or loss of visual acuity by 5 years. DESIGN:Prospective cohort study within a randomized clinical trial of oral supplements. PARTICIPANTS:The AREDS participants whose eyes were phakic at baseline and free of late age-related macular degeneration throughout the study. METHODS:Baseline and annual lens photographs of AREDS participants (n = 3466/4757; 73%) were graded for severity of cataracts using the AREDS system for classifying cataracts from photographs. Clinical examinations conducted semiannually collected data on cataract surgery and visual acuity. Association of the change in lens opacities at 2 years with t

SUBMITTER: Indaram M 

PROVIDER: S-EPMC4414714 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature